ISSCR News
New Podcast Episode. Building a Better Barrier: Modeling the Human gut Epithelium
The human intestinal epithelial barrier comprises diverse proliferative, secretory and absorptive cell types that facilitate nutrient digestion and absorption and protect against harmful environmental agents. The barrier and its function can vary between individuals due to genetic differences thus impact processes such as digestion, drug metabolism, and drug sensitivity. Our guests today investigated the effect of diverse culture conditions on the cell type composition, gene expression profiles, and maturation status of human pluripotent stem cell-derived intestinal epithelial cells in three different model systems. Their research provides insight into the relevant conditions and systems for modeling specific intestinal functions and highlights the importance of personalized intestinal model systems.
The ISSCR, Society for Developmental Biology, and the Allen Institute to Host First Collaborative Scientific Symposium
The event will take place 23-25 September 2026 in Seattle, USA
For the first time, the International Society for Stem Cell Research (ISSCR), the Society for Developmental Biology (SDB), and the Allen Institute are collaborating to present a three-day scientific symposium led by early-career scientists. The Stem Cell & Developmental Biology Early Career Symposium is designed to nurture the next generation of researchers and provide a platform for professional growth while fostering collaboration at the intersection of developmental biology and stem cell science.
Scientists Use Stem Cells to Move Closer to Large-Scale Manufacturing of Platelets
Platelets are small, disc-shaped cell fragments in the blood that are essential to stop bleeding and to initiate blood clotting after injury. Platelet transfusions in patients with severe trauma or medical conditions, including bone marrow disease, leukemia, or sepsis, can be lifesaving. Despite being a standard clinical practice, platelet transfusions face issues related to the availability of blood donations from which platelets are isolated, the relatively short shelf life of purified platelets, and the risk of an immune response in patients receiving platelets from unmatched donors.
The ISSCR Holds Second Meeting With UK Regulators on the Use of AI to Develop Stem Cell Therapies
The International Society for Stem Cell Research (ISSCR) held its second Broader Scope Scientific Advice meeting with the United Kingdom’s Medicines and Healthcare products Regulatory Agency (MHRA) on October 29, 2025, focusing on the use of artificial intelligence (AI) in developing stem cell therapies.
The session explored key topics including the current state and challenges of AI, machine learning, and digitalization systems for automation in cell and gene therapy; applications of AI in autologous iPSC-derived RPE cell therapy; and AI-based image analysis for in-process characterization and decision-making during iPSC generation.
The ISSCR Guide To Stem Cell Treatments Now Available in Portuguese
The ISSCR is now pleased to make the Guide to Stem Cell Treatments available in Portuguese. The comprehensive resource is designed to empower patients, advocates, healthcare providers, friends, and family members with the necessary information to make well-informed decisions regarding stem cell treatments, alongside their primary care physicians or specialists.
The translation of this guide was provided by Inês Figueira, José Manuel Inácio, Liliana Bernardino, Ana Paula Terrasso, Susana Solá, Maria Arez and João Camões dos Santos.
The new version is available for download and sharing is encouraged to help raise awareness and understanding of stem cell treatments. Together, we can contribute to the safe and effective delivery of the potential that stem cell research holds for patients worldwide.
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